At the Advances in Genome Biology and Technology (AGBT) General Meeting 2026 in Orlando, Florida, Volta Labs announced the launch of the Callisto Complete Kit for DNA EF Library Preparation.
The new kit delivers fully automated, PCR-free whole genome sequencing (WGS) by pairing premium chemistry with push-button automation.
Whole genome sequencing is expanding across clinical research and translational labs. PCR-free workflows are increasingly preferred because they:
The trade-off? PCR-free library prep demands precision. Manual workflows struggle to deliver consistent results at scale.
The Callisto Complete Kit combines Watchmaker Genomics DNA EF chemistry with Volta’s digital fluidics automation.
Together, they enable:
The system is designed for mid-throughput labs that need reliability without the complexity of ultra-high-throughput infrastructure.
“We designed Callisto to make sequencing sample preparation simpler and more accessible,” said Udayan Umapathi, CEO of Volta Labs.
With the new kit, labs can run PCR-free WGS workflows in a push-button format, while freeing technical staff for higher-value work.
According to Trey Foskett, CEO of Watchmaker Genomics:
PCR-free WGS requires both high-performance chemistry and workflow precision. The Callisto Complete Kit delivers both—without requiring high-throughput scale.
This makes it well-suited for clinical and translational environments where consistency matters more than sheer volume.
To mark the launch, Volta Labs and Watchmaker Genomics hosted a joint in-suite presentation at AGBT 2026 on February 24 at 8:30 a.m., held in the Fulton Suite.
Volta Labs is rethinking sequencing sample preparation through:
The Callisto platform supports whole-genome, targeted, and custom NGS applications. Volta Labs is headquartered in Boston.
Watchmaker Genomics develops high-performance tools for genomic research and clinical applications.
Its expertise spans:
The company focuses on accuracy, efficiency, and cost-effective molecular analysis.
Bottom line: The Callisto Complete Kit lowers the barrier to PCR-free WGS by combining elite chemistry with true automation—without forcing labs into high-throughput complexity.