Botanic Healthcare Publishes Clinical Data Showing Superior Bioavailability of Lipomac Liposomal Vitamin C
Botanic Healthcare has published new human clinical data demonstrating the superior bioavailability of Lipomac, its clinically engineered liposomal vitamin C, developed using proprietary DFS Technology.
The study provides direct pharmacokinetic evidence that Lipomac delivers significantly higher systemic exposure than conventional vitamin C formulations.
Clinical study design at a glance
The study was conducted as a randomized, open-label, crossover trial in 12 healthy adult subjects.
Participants received:
Lipomac liposomal vitamin C
Conventional non-liposomal vitamin C
Pharmacokinetic parameters were then directly compared within the same subjects.
Key clinical findings
The results showed clear advantages for Lipomac:
Significantly higher systemic vitamin C exposure
Improved gastrointestinal transit
Prolonged circulation time in plasma
These findings confirm that Lipomac overcomes the absorption ceiling commonly associated with conventional vitamin C.
Why liposomal delivery matters?
Traditional vitamin C is highly vulnerable to:
Acidic gastric conditions
Enzymatic degradation
Limited intestinal uptake
Liposomal delivery addresses these challenges by:
Encapsulating vitamin C in biocompatible phospholipid vesicles
Protecting it from digestive degradation
Enhancing intestinal absorption
Improving delivery into systemic circulation
The study offers human clinical validation of liposomal technology as a scalable nutraceutical delivery platform.
DFS Technology and the Lipsobio platform
Lipomac is developed using Botanic Healthcare’s patented DFS Technology, designed to:
Stabilize sensitive actives
Enable targeted delivery
Maximize biological performance
Lipomac is part of Lipsobio, Botanic Healthcare’s advanced liposomal ingredient portfolio, which spans:
Vitamins
Minerals
Nutraceuticals
Botanical actives
Each ingredient is authenticated using:
Cryo-EM and TEM imaging
Nanoscale structural mapping
Encapsulation and stability profiling
In-vitro absorption studies
Human clinical data
Scientific validation from leadership
“These findings validate the core scientific engineering behind DFS Technology,” said Dr. H. N. Shivaprasad, Chief Scientific Officer at Botanic Healthcare. “They reinforce the measurable performance advantages of liposomal formats.”
Strengthening evidence-driven nutraceutical development
The publication further strengthens Botanic Healthcare’s evidence-backed ingredient portfolio and highlights its commitment to translating advanced delivery science into clinically meaningful health solutions for global partners.