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  3. Botanic Healthcare Publishes Clinical Data Showing Superior Bioavailability Of Lipomac Liposomal Vitamin C
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  • 23 Jan 2026
  • Admin
  • News Article

Botanic Healthcare Publishes Clinical Data Showing Superior Bioavailability of Lipomac Liposomal Vitamin C

Botanic Healthcare has published new human clinical data demonstrating the superior bioavailability of Lipomac, its clinically engineered liposomal vitamin C, developed using proprietary DFS Technology.

The study provides direct pharmacokinetic evidence that Lipomac delivers significantly higher systemic exposure than conventional vitamin C formulations.

Clinical study design at a glance

The study was conducted as a randomized, open-label, crossover trial in 12 healthy adult subjects.

Participants received:

  • Lipomac liposomal vitamin C
  • Conventional non-liposomal vitamin C

Pharmacokinetic parameters were then directly compared within the same subjects.

Key clinical findings

The results showed clear advantages for Lipomac:

  • Significantly higher systemic vitamin C exposure
  • Improved gastrointestinal transit
  • Prolonged circulation time in plasma

These findings confirm that Lipomac overcomes the absorption ceiling commonly associated with conventional vitamin C.

Why liposomal delivery matters?

Traditional vitamin C is highly vulnerable to:

  • Acidic gastric conditions
  • Enzymatic degradation
  • Limited intestinal uptake

Liposomal delivery addresses these challenges by:

  • Encapsulating vitamin C in biocompatible phospholipid vesicles
  • Protecting it from digestive degradation
  • Enhancing intestinal absorption
  • Improving delivery into systemic circulation

The study offers human clinical validation of liposomal technology as a scalable nutraceutical delivery platform.

DFS Technology and the Lipsobio platform

Lipomac is developed using Botanic Healthcare’s patented DFS Technology, designed to:

  • Stabilize sensitive actives
  • Enable targeted delivery
  • Maximize biological performance

Lipomac is part of Lipsobio, Botanic Healthcare’s advanced liposomal ingredient portfolio, which spans:

  • Vitamins
  • Minerals
  • Nutraceuticals
  • Botanical actives

Each ingredient is authenticated using:

  • Cryo-EM and TEM imaging
  • Nanoscale structural mapping
  • Encapsulation and stability profiling
  • In-vitro absorption studies
  • Human clinical data

Scientific validation from leadership

“These findings validate the core scientific engineering behind DFS Technology,” said Dr. H. N. Shivaprasad, Chief Scientific Officer at Botanic Healthcare. “They reinforce the measurable performance advantages of liposomal formats.”

Strengthening evidence-driven nutraceutical development

The publication further strengthens Botanic Healthcare’s evidence-backed ingredient portfolio and highlights its commitment to translating advanced delivery science into clinically meaningful health solutions for global partners.

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