Alamar Biosciences Launches 5-Plex Blood Assay for Alzheimer’s Research
Alamar Biosciences has launched the NULISAqpcr AD 5-plex Assay, a Research Use Only (RUO) solution designed to advance blood-based research in Alzheimer’s disease and related neurodegenerative disorders.
The assay enables simultaneous quantitative measurement of five critical biomarkers from a single blood or plasma sample.
What the Assay Measures?
The 5-plex panel aligns with Alzheimer’s Association–recommended biomarkers and includes:
BD-pTau217 – marker of tau pathology
Amyloid-beta 42 (Aβ42) – indicator of amyloid burden
Neurofilament light chain (NfL) – marker of neurodegeneration
Glial fibrillary acidic protein (GFAP) – indicator of neuroinflammation
APOE4 carrier status – strongest known genetic risk factor for Alzheimer’s
Together, these markers provide a comprehensive molecular snapshot of disease biology.
Why This Matters?
Most current approaches rely on single-plex assays, requiring multiple tests to capture disease complexity. The NULISAqpcr AD 5-plex Assay consolidates this process into one multiplexed workflow, offering:
Ultra-high sensitivity and specificity
Reduced sample volume requirements
Streamlined, scalable testing
A more holistic view of disease pathology
Its application extends beyond Alzheimer’s to other cognitive and neurodegenerative disorders.
Leadership Perspective
Dr. Yuling Luo, founder, chairman and CEO of Alamar, described the launch as a milestone in precision proteomics.
He emphasized that combining critical protein targets into one assay helps accelerate early detection, screening, and precision diagnosis.
Dr. Steven Williams, chief scientific officer, highlighted the growing role of blood-based biomarkers.
He noted that multiplexed measurement delivers richer biological insight than isolated biomarker testing.
Availability
The NULISAqpcr AD 5-plex Assay is available immediately as a service through Alamar’s Technology Access Programme.
About Alamar Biosciences
Alamar Biosciences is a privately held life sciences company focused on precision proteomics for early disease detection.
Its platform is built on proprietary NULISA technology and the ARGO HT System, designed to overcome sensitivity and scalability limitations of existing proteomic tools.